Primary squamous cell carcinoma of kidney: a case report

Abstract

Neoplasms of the kidney are most commonly adenocarcinomas. Squamous cell carcinoma of renal pelvis and ureter are very rare and account for 6-15% of all renal tumours. Very few such cases have been reported. Most are associated with calculus disease or hydronephrosis. Our case was a 44year old female having pain & lump in right flank since six months. Contrast CT abdomen showed an 8.8x8.8x6.4 cm renal upper pole mass with well-defined rounded calcification invading directly into the liver. There was no calculus or hydronephrosis. Ultrasound guided tru-cut biopsy was inconclusive, showing only dysplastic cells. On exploration, the mass was found to be arising from postero-superior pole of right kidney, with direct invasion into the liver. A nephroureterectomy with wedge resection of liver was performed. Histopathology of the specimen showed well differentiated squamous cell carcinoma of renal pelvis extending into liver.