Abstract
Primary retroperitoneal mucinous cystadenomas are extremely rare. They are unattached to the ovary and found almost exclusively in women. The pathogenesis of such neoplasms remains uncertain. Herein, we describe a 52-year-old woman who had an en bloc resection of a large retroperitoneal cystic tumor. Microscopic examination of the lining epithelial cells showed features of mesothelial cells in addition to a benign mucinous cystadenoma. These findings suggest that the tumor developed from mucinous metaplasia of the coelomic mesothelium. The mesotheliallike epithelium was positive for estrogen receptors, implicating its role in tumor promotion and the almost exclusive occurrence of such tumors in women.
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