Abstract

Primary pulmonary Hodgkin's lymphoma (PPHL) is an uncommon disease. This entity is different from Hodgkin’s lymphoma with parenchymal or nodal lung involvement. In this report, we highlight the case of a young female presenting with a six-month history of a productive cough and constitutional B symptoms. Imaging showed cavitary lesions in the right-upper and right-middle lobes. The initial comprehensive infectious workup was negative. Histopathology and immunochemistry confirmed the diagnosis of PPHL. PPHL is an uncommon etiology of cavitary lung lesions. Despite its diagnostic difficulties, awareness of such a disease is crucial, given its high rate of response to treatment, especially in the young population.

Highlights

  • Pulmonary involvement in Hodgkin’s lymphoma is common (15%-40% of cases), primary pulmonary Hodgkin’s lymphoma (PPHL) is a very rarely documented presentation of Hodgkin’s disease consisting of

  • Cavitations are not uncommon during the course of chemotherapy for PPHL, they are exceptionally rare at the time of diagnosis

  • We report a case of PPHL that presents as a cavitary mass associated with constitutional B symptoms in a young, previously healthy, female

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Summary

Introduction

Pulmonary involvement in Hodgkin’s lymphoma is common (15%-40% of cases), primary pulmonary Hodgkin’s lymphoma (PPHL) is a very rarely documented presentation of Hodgkin’s disease consisting of

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