Abstract

BackgroundPrimary pulmonary artery sarcomas are rare malignant vascular tumors and carry a very poor prognosis. Due to overlapping clinical and radiological features, the differentiation between pulmonary artery thromboembolism and pulmonary artery sarcoma can be challenging.Case presentationWe herein present clinical, radiological and pathological features of primary pulmonary artery high grade sarcoma (angiosarcoma) in a 59-year-old male. The patient presented with a history of breathlessness on exertion of 2-months duration and was misdiagnosed as massive pulmonary thromboembolism on initial CT imaging.ConclusionGreat similarity with significant degree of overlap in clinical and radiologic presentation makes differentiation of pulmonary artery sarcomas and thromboembolism a diagnostic challenge. Even though they are exceptionally rare, one should always consider it as differential diagnosis especially in cases with atypical clinical or imaging presentation.

Highlights

  • Primary pulmonary artery sarcomas are rare malignant vascular tumors and carry a very poor prognosis

  • Primary pulmonary angiosarcomas usually manifest as multiple bilateral nodules

  • MRI scores over CT in detecting the subtle post-contrast heterogeneity that helps in ruling out bland pulmonary artery thrombosis and provides more accurate delineation of the extent of local disease than CT [2, 3]

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Summary

Conclusion

Great similarity with significant degree of overlap in clinical and radiologic presentation makes differentiation of pulmonary artery sarcomas and thromboembolism a diagnostic challenge.

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