Abstract

Primary pleural squamous cell carcinoma is very rare, and there is a lack of experience in the diagnosis and treatment of this condition. An asymptomatic 75-year-old man was referred to us after a right pleural nodule was found on computed tomography during a routine health examination. He underwent surgery for his pleural tumor twice over the following 2 years. Histopathological examination eventually led to a diagnosis of primary pleural squamous cell carcinoma.

Highlights

  • Primary pleural squamous cell carcinoma (SCC) is very rare [1]

  • As patients are generally asymptomatic in the early stage and computed tomography (CT) shows local pleural thickening or small nodules, primary pleural SCC is misdiagnosed as localized mesothelioma

  • Early primary pleural SCC may be misdiagnosed as localized mesothelioma, especially solitary fibrous tumor (SFT) of the pleura

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Summary

Background

Primary pleural squamous cell carcinoma (SCC) is very rare [1]. A review of the literature did not find any recently reported cases. Case presentation In August 2009, a 75-year-old man (Chinese, ethnic Han) was referred to our clinic after a right pleural nodule was found on chest CT during a routine health examination. He was asymptomatic, and physical examination was. En bloc resection of the tumor was performed, including the chest wall, pleura, part of the right upper lobe, part of the fourth and fifth ribs, and tissues of the intercostal space. Postoperative histopathological examination revealed areas of pleomorphic tumor cells with large nuclei and reduced cytoplasm These features were consistent with stage I SCC (Figure 4). CT showed that the operation area was in good condition (Figure 5)

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