Abstract
Liposarcoma is the most common soft tissues sarcoma in adults. Pleiomorphic liposarcoma (PLS) is a rare subtype of liposarcoma with the highest malignancy rate. In this paper we present a rare case of pleiomorphic liposarcoma of the colon and the management of the disease.
Highlights
Liposarcoma is the most common soft tissues sarcoma in adults
Pleiomorphic liposarcoma of the colon is extremely rare with high recurrence and poor prognosis
We present here a rare case of primary colic pleiomorphic liposarcoma and the discussion of the treatment and follow-up of the patient
Summary
This report describes an extremely rare case of descending colon pleiomorphic liposarcoma. The survival-rate of the patients and recurrence of the disease are related to different factors: the grading of the tumor, the subtype of the tumor, the margins of the resection, the presence or not of metastasis and the tumor size [12]. High-grade liposarcoma have higher rates of distant metastasis and local recurrence [14,16,17] In this case, we are interested in the pleiomorphic type which is very rare, and accounts for only 5% to 10% of lipomatous tumors [9,16]. There are new recommendations concerning soft tissues and visceral sarcomas from the ESMO-EURACAN group (European Society for Medical Oncology- European Reference Network for rare adult solid cancers) [20] These guidelines are for the diagnosis, treatment and follow-up of the patients. If the removal of the tumor is not possible or if the patient is not able to undergo a second surgery, we would have to discuss about chemotherapy or radiotherapy [21,22,23]
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