Primary outcomes of one-stage repair for interrupted aortic arch at Vietnam National Children’s Hospital

Abstract

Objective: This study focuses on primary outcomes of one-stage repair for interrupted aortic arch (IAA) from a single institution from Vietnam. Methods: Between 2012 and September 2017, 27 patients underwent one-stage repair in Children Heart Center, National Hospital of Pediatrics. Kaplan-Meier survival analysis plotted survival and freedom from reoperation curves from follow-up data. Results: Median age was 53 days (range, 9 days to 5 months) and weight was 3.5 kg (range, 2.3 to 6.5 kg). IAA type A in 16 cases (59.3%), IAA type B in 11 case (40.7%). Associated anomalies were ventricular septal defect in 20 (74.1%), aortopulmonary window in 4 (14.8%), truncus arteriosus in 3 (11.1%). Fourteen patients (51.9%) have left ventricular outflow tract obstruction (LVOTO). Median follow-up was 17 months (range, 1 day to 71 months). Survival rates at 30 days, 1 year and 5 years were 81.5%, 77,6% and 77,6% respectively. There were 5 early deaths in hospital, 4 deaths related to nosocomial infection with positive results in blood culture or endotracheal tube, the other was sudden death. One late death after 4 months was caused by severe pulmonary artery stenosis after total repair of interrupted aortic arch associated with truncus arteriosus. There were 5 late reoperations or balloon angioplasty, reoperation for LVOTO in 3, right ventricular outflow tract reconstruction in 1, the other required balloon angioplasty for recurrence of aortic arch stenosis. Conclusion: Primary outcomes of one-stage repair for interrupted aortic arch are safe in our institution. Long-term outcomes evaluation is needed for this complex congenital heart disease.