Primary orbital lymphoma: staging by computed tomographic scanning.

Abstract

Primary orbital lymphoma is a rare form of extranodal lymphoma and accounts for only 1% of all orbital tumours (Calle et al, 1975). Recently reported series have dealt principally with the clinical and radiotherapeutic aspects of the disease, including risk factors for the development of systemic lymphoma (Knowles & Jakobiec, 1980; Fitzpatrick & Macko, 1984; Barthold et al, 1986; Gordon et al, 1986). Published data on the results of staging investigations have included little information on computed tomographic (CT) scanning (Henk, 1982; Bessell et al, 1989). Most patients undergo extensive investigation including a full blood count and erythrocyte sedimentation rate (ESR), liver function tests, bone marrow examination, chest radiography and, in recent years, abdominal and thoracic CT. We have retrospectively studied a group of patients with primary orbital lymphoma, with particular reference to their staging investigations and to the factors affecting the development of systemic disease. All patients with primary orbital lymphoma who were referred for abdominal and thoracic CT were included. This group did not include those patients with known non- Hodgkin's lymphoma and secondary orbital involvement. Many of these patients were referred by Mr J. Wright at the Orbital Clinic, Moorfields Eye Hospital for further management after initial investigation including open biopsy, pathology and orbital CT scanning. Patients underwent a full clinical examination, blood count and ESR, liver function tests, bone marrow trephine and chest radiography.