Abstract
A 43-year-old woman had unilateral exophthalmos caused by primary orbital Ewing sarcoma. Specialized immunohistochemical stains, primarily MIC-2 (CD99), aided in the diagnosis of Ewing sarcoma. Twenty-two months after radiotherapy and multiagent chemotherapy, the patient remained tumor free. To our knowledge, this is the first reported case of orbital Ewing sarcoma to present in an adult beyond the fourth decade of life.
Highlights
43-year-old woman had unilateral exophthalmos caused by primary orbital Ewing sarcoma
Of neuroectodermal origin, Ewing sarcoma can be confused with other small round cell tumors
We report a unique case of orbital Ewing sarcoma in a 43year-old woman and the application of MIC-2 (CD99) in diagnostic analysis
Summary
Twenty-two months after radiotherapy and multiagent chemotherapy, the patient remained tumor free. To our knowledge, this is the first reported case of orbital Ewing sarcoma to present in an adult beyond the fourth decade of life. Orbital involvement is rare.[1,2,3] This tumor typically affects white males under age 20 years.[3] Of neuroectodermal origin, Ewing sarcoma can be confused with other small round cell tumors. Immunohistochemical studies are important for establishing an accurate diagnosis.[3,4,5,6] We report a unique case of orbital Ewing sarcoma in a 43year-old woman and the application of MIC-2 (CD99) in diagnostic analysis
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