Abstract
Primary neuroendocrine carcinoma of the kidney is an extremely rare neoplasm. We report a case of primary renal neuroendocrine carcinoma with neck lymph node metastasis. Abdominal CT scan showed an 8 cm infiltrating mass with central necrosis over the upper pole of the left kidney. A CT scan of the neck revealed multiple necrotic lymph nodes on both sides of the supraclavicular fossa and left lower posterior triangle. Radical nephrectomy was performed after chemotherapy. Histologically, the tumor revealed neuroendocrine carcinoma of the kidney. Immunohistochemically, the tumor cells demonstrated immunoreactivity for AE3, chromogranin and synaptophysin. Local recurrence was noted after surgery and the patient died8 months after presentation.
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