Abstract
Key Clinical MessageOur case highlights a series of bone marrow biopsies from a patient with primary myelofibrosis. Over time, this patient developed an unusual fatty appearance to his marrow, confirmed on multiple biopsies. This finding was supported by a quantitative fat MRI sequence that also shows a fatty appearance to the marrow.
Highlights
Key Clinical Message Our case highlights a series of bone marrow biopsies from a patient with primary myelofibrosis
A 54-y ear-old man was diagnosed with MPL mutated, primary myelofibrosis in 2004 with a hypercellular marrow, MF-2 fibrosis with megakaryocytic atypia, peripheral leukoerythroblastosis, splenomegaly, and an elevated lactate dehydrogenase
CONFLICT OF INTERESTS Dr Talpaz is on the advisory board for CTI Biopharma and Gilead
Summary
Moshe Talpaz, University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI, USA. Key Clinical Message Our case highlights a series of bone marrow biopsies from a patient with primary myelofibrosis. This patient developed an unusual fatty appearance to his marrow, confirmed on multiple biopsies.
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