Abstract
Primary urinary bladder amyloidosis is a rare disorder of protein metabolism characterized by the extracellular deposition of fibrillin. To date, fewer than 200 cases have been reported in the literature. We herein present a case of 59-year-old female with primary multifocal recurrent urinary bladder amyloidosis. The patient was treated with a new method (laser therapy) mentioned for the first time in the literature. After 18 months of treatment, the patient has no complaints. Our case illustrates a new procedure in the treatment of primary multifocal bladder amyloidosis.
Highlights
Amyloidosis is a heterogeneous group disorder characterized by the extracellular deposition of eosinophilic fibrillar protein in various tissues and organs [1]
We present the first rare case in Syria of recurrent multifocal primary urinary bladder amyloidosis (PUBA) treated with laser therapy for the first time in the medical literature
A 59-year-old Syrian female was admitted with a 2-month history of gross hematuria associated with lower urinary tract symptoms. ere were no systemic symptoms. e hematuria was red in color, fresh, and intermittent with no clotting
Summary
Amyloidosis is a heterogeneous group disorder characterized by the extracellular deposition of eosinophilic fibrillar protein (amyloid protein) in various tissues and organs [1]. In 1897, Solomin described the first clinical case of bladder amyloidosis (BA) at autopsy [2]. Ere are two forms of BA: primary urinary bladder amyloidosis (PUBA) and secondary (commonly associated with chronic inflammatory conditions) [1]. Gross hematuria with irritative lower urinary tract symptoms is the most prominent in PUBA. We present the first rare case in Syria of recurrent multifocal PUBA treated with laser therapy for the first time in the medical literature.
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