Abstract

View Large Image Figure Viewer Download Hi-res image View Large Image Figure Viewer Download Hi-res image View Large Image Figure Viewer Download Hi-res image An asymptomatic 59-year-old woman was referred for colorectal cancer screening. She had no significant medical history and was taking no medications except multivitamins. Colonoscopy revealed multiple lesions, at 7 different locations (from the rectum to the proximal transverse colon), all of which appeared similar; they were polypoid, had a normal-appearing overlying mucosa, and measured 5 to 15 mm in size (A, B). Three of these lesions were removed by using a polypectomy snare, and the others were biopsied. Histology was similar for all of the lesions: non-Hodgkin lymphoma; follicular center cell lymphoma; Grade 2, follicular pattern (C, H&E, orig. mag. ×4, D, Bcl-2, orig. mag. ×10). CT scanning of the abdomen and pelvis showed retroperitoneal, iliac, and inguinal adenopathy. She was treated with 4 months of chemotherapy, which consisted of rituximab, cyclophosphamide, vincristine, and prednisone. Colonoscopy was repeated 2 months after completion of chemotherapy; all the lesions had disappeared, and the entire colon showed normal mucosa. Repeat CT scanning revealed resolution of the lymphadenopathy. View Large Image Figure Viewer Download Hi-res image View Large Image Figure Viewer Download Hi-res image

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