Primary mucinous skin cancer: A case report and review of the literature

Abstract

Primary mucinous carcinoma of the skin (PMCS) is an extremely uncommon skin cancer originating from sweat glands. We present a case of a male patient diagnosed with PMCS who was initially misdiagnosed with benign sebaceous cysts. A 62-year-old male patient presented to a private clinic with a chief complaint of a slowly progressing nodule located under his lower lip for the past two years; The nodule was locally excised . The histopathology analysis yielded a diagnosis of mucinous carcinoma with a positive circumferential margin. Reexcison was performed, and the final histopathology result was a small nest of mucinous carcinoma with a negative surgical margin. He underwent thorough investigation, including gastroduodenoscopy, colonoscopy, and computerized tomography (CT) scans of the chest, abdomen, and pelvis, and found no signs of primary tumor. He was discharged from our hospital and educated to follow up closely for local recurrence. This paper illustrates the rarity of this disease, its vague presentation, and a brief review of diagnosis and treatment.