Abstract
A 60 year old male, chronic smoker and alcoholic since 30 years came with complaints of gross hematuria since 2 days. Clinically he was alright. CT scan showed a bladder mass reaching outside the serosa with no nodal involvement. Wide local excision was done with partial cystectomy. Growth was found on the dome of the bladder and was sent for histopathology. Sections showed tumour cells arranged in papillary pattern and lined by pseudostratified tall columnar epithelium filled with mucin and goblet cells at places. Intervening stroma shows abundant extracellular mucin, areas of necrosis and tumour cells showing malignant features with few areas with signet cells. Mucosal margins were also involved. Case diagnosed as Well differentiated mucinous Adenocarcinoma- Bladder. DOI: 10.21276/APALM.1610
Highlights
Bladder carcinoma is the ninth most common cancer worldwide
Urothelial carcinoma accounts for 9095% of bladder while squamous cell carcinoma and adenocarcinoma account for 3% and 2% respectively.[1]
Mucosal margins were involved by tumour floating in pools of mucin The case was diagnosed as well differentiated Mucinous Adenocarcinoma- Bladder
Summary
Bladder carcinoma is the ninth most common cancer worldwide. Urothelial carcinoma accounts for 9095% of bladder while squamous cell carcinoma and adenocarcinoma account for 3% and 2% respectively.[1]. On per rectal examination prostate was normal. Alkaline phosphatase and lactate dehydrogenase levels were normal. CT scan showed a bladder mass reaching outside the serosa with no nodal involvement. A growth seen on the dome of the bladder and was sent for histopathology. Cut surface showed a single solid white firm to hard exophytic growth measuring 4cm at the dome of the bladder not extending to the peritoneal surface. Sections showed tumour cells arranged in papillary and glandular pattern(figure 1 ). Individual tumour cells were columnar showing high N:C ratio, hyperchromasia, coarse chromatin and intracellular mucin. Few areas showed signet ring cells (figure 2) and denuded tumour. Mucosal margins were involved by tumour floating in pools of mucin (figure 3) The case was diagnosed as well differentiated Mucinous Adenocarcinoma- Bladder
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