Abstract
IntroductionLiposarcoma is the most commonly diagnosed soft tissue sarcoma in adults and occurs predominantly in the lower limbs and retroperitoneum. Primary mediastinal liposarcomas are rare.They are often asymptomatic and when growing to large size the presenting symptoms are related to direct invasion or compression of other thoracic organs such as the heart, great vessels and lung.Case presentationA case of a 68-year-old man with primary mediastinal liposarcoma involving the diaphragm and pericardium and successfully managed by complete surgical excision is presented. The patient's postoperative course was uneventful with no evidence of recurrence 9 months after the operation.ConclusionSurgical removal is the optimal treatment for a mediastinal liposarcoma. If the entire tumor can not be resected, surgical debulking often results in symptomatic relief. International literature has demonstrated that recurrent disease occurs and therefore a long-term careful follow up is required.
Highlights
Liposarcoma is the most commonly diagnosed soft tissue sarcoma in adults and occurs predominantly in the lower limbs and retroperitoneum
A case of primary mediastinal liposarcoma involving the diaphragm and pericardium, which was successfully managed by complete surgical excision is presented here
Surgical removal is the optimal treatment for a mediastinal liposarcoma, as in other sites
Summary
Surgical removal is the optimal treatment for a mediastinal liposarcoma, as in other sites. Radiotherapy and chemotherapy may be added as adjuncts to surgical excision but liposarcomas seem to have low sensitivity [9]. Recurrence is common in deep-seated liposarcomas and it becomes apparent within the first 6 months in most cases, but it may be delayed for 5 or 10 years following the initial excision [10]. Authors' contributions NB was involved in the case directly (surgeon) and drafted part of the manuscript. GS, ES, EK and TB took part in the care of the patient and contributed in carrying out the medical literature search and preparation of the manuscript. CT participated in the care of the patient and had the supervision of this report. Consent Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal
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