Abstract
Metastatic tumours of pleura are the most common malignant tumours causing malignant pleural effusion. Lungs are the most common primary sites. Primary pleural tumours are rarely seen and diffuse malignant mesothelioma is the most common malignant tumour of pleura. Primary malignant neuroendocrine tumour of pleura is not reported in the literature. Here, we report a rare case of primary malignant neuroendocrine tumour of pleura in a fifty-two-year-old, nonsmoker female who presented with right-sided pleural effusion and ipsilateral, dull aching chest pain. Clinical presentations of inflammatory lesions like tuberculous pleuritis and benign and malignant neoplasms of pleura are indistinguishable; hence, fluid cytology, pleural biopsy, and immunohistochemistry are necessary for exact tissue diagnosis of the tumours, which is mandatory for correct treatment and prognostic assessment.
Highlights
Metastatic pleural tumours are by far the most common malignant neoplasms of the pleura and greatly outnumbering the primary pleural tumours
Primary pleural tumours other than mesothelioma account for less than 1% of all pleural tumours and are rarely reported in the literature, causing diagnostic and management dilemma [1]
Malignant pleural tumours mainly present with pleural effusion or pleural nodules
Summary
Metastatic pleural tumours are by far the most common malignant neoplasms of the pleura and greatly outnumbering the primary pleural tumours. Among the primary pleural malignancies, diffuse malignant mesothelioma is the most common primary malignant tumour of the pleura. Primary pleural tumours other than mesothelioma account for less than 1% of all pleural tumours and are rarely reported in the literature, causing diagnostic and management dilemma [1]. In most cases, they are diagnosed as incidental during histopathological examination of pleural tissue, obtained by closed pleural biopsy or obtained under thoracoscopic visualization. We report the first case of primary malignant neuroendocrine tumour of pleura in a fifty-twoyear-old female, presenting with isolated right-sided pleural effusion
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