Primary Malignant Bones Cancers in Cote d’Ivoire: Epidemiological and Histopathological Aspects

Kone Samba,Bana Abdoulaye,R Kouakou Konan,Eti Edmond,Agoh Serge,J N’Dah Kouame,Doukoure Brahima,A Ngandjeu Nawé

doi:10.4236/ojpathology.2018.82006

Abstract

Primary bones cancers are rare and ubiquitous malignant tumors. Aim: Our study aimed was to describe the epidemiological and histopathological aspects of primary malignant bone cancers in Ivory Coast. Material and method: This is a retrospective and descriptive study of primary malignant bone cancers diagnosed over the period 1990 to 2013 (24 years). The studied parameters were: epidemiological aspects (frequency, age, sex, topography) and histological aspects. Results: Over the study period, primary malignant bone cancers accounted for 1.93% (n = 228) of cancers. The average age was 27.02 years with extremes of 2 and 85 years. The sex ratio was 1.65. They were in the skull and maxilla in 43.9% (n = 105), lower limbs (23.8%), spine and ribs (19.8%), pelvis (5.3%) and upper limbs (2.3%). The clinic was dominated by pain and alteration of general state. Radiology was variable depending on the histological type. In children, primary malignant bone cancers were found in the maxillary (77.9%) and the lower limb (15.8%). Burkitt’s lymphomas represented 36.4% (n = 66) of the histological types followed by 22.4% osteosarcomas (n = 51). In adults at histology, sarcomas were the most common (10%), followed by cancers of the hematopoietic and lymphatic organs (8.09%). Conclusion: Primary malignant bone cancers are rare in Ivory Coast. They most often affect male children with maxillofacial involvement and predominant lower extremity. Burkitt’s lymphoma and osteosarcoma are the often diagnosed histological types.

Highlights

Primary bones cancers are relatively rare malignant tumors, mainly affecting the big child, the adolescent and the young adult
Radiology was variable depending on the histological type
Radiology quite variable depending on the histological type

Summary

Introduction

Primary bones cancers are relatively rare malignant tumors, mainly affecting the big child, the adolescent and the young adult. They represent about 0.2% of adult cancers and 5% of childhood cancers [1] [2]. Their diagnosis is usually based on anatomopathological examination correlated with clinical and radiographic data. These cancers prognosis is often fatal in most countries. Current multidisciplinary therapeutic strategies have improved the prognosis over the last twenty years in developed countries [1] [3]. For decades some authors [4] [5] have issued alerts on the extent of the general cancer pathology in our country

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