Primary liver cell carcinoma associated with biliary cirrhosis due to congenital bile duct atresia: First report of a case

Abstract

A case of primary hepatic carcinoma superimposed on biliary cirrhosis due to congenital biliary atresia in a 3-year-old patient is reported. The patient presented obstructive jaundice from 3 days of age, signs of biliary cirrhosis and hepatic insufficiency, and malnutrition. Postmortem examination revealed liver cell carcinoma primary in the right lobe of the liver with pulmonary metastasis, advanced biliary cirrhosis, and complete absence of extrahepatic bile ducts. No case of the occurrence of hepatoma in a child with biliary cirrhosis due to biliary atresia has been reported previously.