Abstract
Primary laryngeal tuberculosis is rare. It can manifest as a malignancy delaying the diagnosis and the therapeutic management. We report the case of a 34-year-old immunocompetent man whose plaints were fever, sweat and dysphonia. There were no adenopathy, nor hepatosplenomegaly. Several blood cultures were negative. Laboratory studies showed an inflammatory syndrome. In addition, the bacteriological examinations of sputum and urine in search of Mycobacterium tuberculosis were negative. Laryngoscopy confirmed the presence of a thickness of the right vocal cord and an ulcer in the hemilarynx. The histological examination revealed tuberculoid granulomas suggestive of tuberculosis. The culture from vocal cord tissue for Mycobacterium tuberculosis was positive. No other focus of tuberculosis was found on X-ray and computed tomography. Treatment by a combination of isoniazid, rifampicin, pyrazinamide induced a total resolution of symptoms.
Highlights
The tuberculosis is an infection due to Mycobacterium tuberculosis
The aim of this study is to demonstrate the diagnosis difficulty of extrapulmonary tuberculosis; as illustrate our case who presents laryngeal tuberculosis mimicking a tumoral origin
The vocal cord and ulcer histological examination revealed inflammatory infiltrates organized in granulomas formed essentially of lymphocytes, epitheloid and giant cells, fibrosis and caseous necrosis, suggestive of tuberculosis and the ziehl-neelsen staining showed acid-alcohol resistant bacilli
Summary
The tuberculosis is an infection due to Mycobacterium tuberculosis. The pulmonary form is the most frequent. Clinical features of tuberculosis have been changed because of the antituberculous drugs availability and various immunosuppressive conditions increase. How to cite this paper: Mahfoudhi, M., et al (2015) Primary Laryngeal Tuberculosis. These conditions have favored the emergence of extrapulmonary forms of tuberculosis implicating rachis, meninges, hypophysis, thyroid, digestive system, larynx. When laryngeal manifestations are associated to pulmonary signs, tuberculosis diagnosis is easy. Primary laryngeal tuberculosis is rare and may manifest as a tumor inducing a delayed diagnosis time [1] [2]. Clinical and endoscopic feature have no specificity in case of primary laryngeal tuberculosis. The aim of this study is to demonstrate the diagnosis difficulty of extrapulmonary tuberculosis; as illustrate our case who presents laryngeal tuberculosis mimicking a tumoral origin
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