Abstract
BackgroundPrimary isolated gastric TB of the cardia presenting as a submucosal tumor is extremely rare.Case presentationA 60-year-old female was admitted to our department; endoscopy revealed a smooth protruding lesion in the gastric cardia. The patient was diagnosed with a gastric cardia stromal tumor and the lesion was seen in muscularis propria by endoscopic ultrasonography (EUS). Endoscopic submucosal dissection (ESD) revealed that the lesion was filled with a milky, white liquid and white granulation tissue. Acid-fast specimen staining was negative. Hematoxylin and eosin staining showed patches of caseating necrosis and granulomatous inflammation. Gene sequencing subsequent to polymerase chain reaction (PCR) analysis of the ESD specimen identified Mycobacterium tuberculosis (M. TB) DNA fragments. The patient was put on ATT for 6 months.ConclusionPrimary isolated gastric TB of the cardia should be suspected in patients without clinical symptoms whose manifestations are similar to those associated with submucosal tumors. TB-PCR may be helpful for further diagnosis.
Highlights
Primary isolated gastric Mycobacterium tuberculosis (TB) of the cardia presenting as a submucosal tumor is extremely rare.Case presentation: A 60-year-old female was admitted to our department; endoscopy revealed a smooth protruding lesion in the gastric cardia
According to previously published case reports and series, gastric TB can be classified into four types: primary gastric TB, gastric TB secondary to pulmonary TB, gastric TB associated with the involvement of other parts of the gastrointestinal tract, and gastric TB in HIV-positive patients [10]
The routes of TB infection in the stomach are unclear [11, 12], and the main causes of isolated or primary gastric TB may be the ingestion of unpasteurized milk infected with bovine TB or a severely immunocompromised condition [13, 14]
Summary
Primary isolated gastric TB of the cardia presenting as a submucosal tumor is extremely rare.Case presentation: A 60-year-old female was admitted to our department; endoscopy revealed a smooth protruding lesion in the gastric cardia. There have been several reported cases of gastric TB mimicking a subepithelial tumor or gastrointestinal stromal tumor, but most cases were mainly located in the antrum of the stomach [3,4,5,6]. Gastric tuberculosis in the cardia of the stomach usually appears like a gastric stromal tumor [4]. We report a case of gastric cardia TB that manifested as a gastric stromal tumor without evidence of pulmonary involvement or other syndromes, except for a BMI < 18 kg/m2.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
