Abstract
BackgroundSclerotic tumours of the calvarial bones are rare and may be due to primary and secondary bone tumours as well as extradural tumours of meningeal origin.Case presentationWe report a case of primary intraosseous meningioma (PIM) which arose in the frontal bone of a 63 year old woman who complained of progressive pain and thickening of the right skull. Radiology showed a large osteosclerotic lesion in the right frontal bone. Histology showed an intraosseous lesion containing dense fibrous tissue in which there were scattered cells that expressed epithelial membrane antigen and progesterone receptor. The tumour was partially resected and 3 years after operation has not recurred.ConclusionsPIM is a rare tumour which needs to be distinguished from primary/secondary osteosclerotic calvarial bone tumours.
Highlights
Sclerotic tumours of the calvarial bones are rare and may be due to primary and secondary bone tumours as well as extradural tumours of meningeal origin.Case presentation: We report a case of primary intraosseous meningioma (PIM) which arose in the frontal bone of a 63 year old woman who complained of progressive pain and thickening of the right skull
We report a case of a primary intraosseous meningioma (PIM), which was markedly osteosclerotic and difficult to distinguish histologically and radiologically from a malignant primary/ secondary bone tumour
Case report A sixty-three year old woman presented with progressive pain and thickening of the right skull frontal bone
Summary
Primary tumours and tumour-like conditions of the cranial vault are rare in both children and adults [1,2,3]. We report a case of a primary intraosseous meningioma (PIM), which was markedly osteosclerotic and difficult to distinguish histologically and radiologically from a malignant primary/ secondary bone tumour. The nature of this rare lesion is discussed and the differential diagnosis of osteosclerotic calvarial tumours reviewed. Plain x-ray films revealed a large, sclerotic lesion involving the right side of the frontal bone of the skull, extending to the unilateral frontal sinus (Fig. 1). After biopsy of the lesion for histological diagnosis (see below), follow-up imaging showed progressive periosteal bone formation on the external table of the calvarium. There were numerous scattered cells with vacuolated cytoplasm and focally
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