Abstract
Primary Intracranial Leiomyosarcoma - Case Report and Principles for Treatment
Highlights
Primary intracranial leiomysarcoma (LMS) is a rare clinical entity
We present a case of a 43 year old male patient with de novo occurrence of intracranial LMS, review the literature and describe principles for a multimodal therapy
Three and six months follow up MRI of the brain and spine showed no recurrence
Summary
Primary intracranial leiomysarcoma (LMS) is a rare clinical entity. We present a case of a patient with primary intracranial LMS ten years after surgical resection of a pilocytic astrocytoma in the posterior fossa and highlight different diagnostic and therapeutical features. Leiomyosarcoma (LMS) is a malignant neoplasm of smooth muscle cells usually with an aggressive growth tendency. Involvement of the central nervous system (CNS) is a very rare clinical entity; most arises with dural attachment[1,2,3]. Cases with spread of LMS into the CNS are reported infrequently[1,4]. We present a case of a 43 year old male patient with de novo occurrence of intracranial LMS, review the literature and describe principles for a multimodal therapy.
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