Abstract
The primary interaction of taurultam with both Escherichia coli (isolated from a urinary tract infection) and mammalian erythrocytes was studied at 37dC. Using E. coli as the adsorbate, the adsorption of taurultam was observed to follow a constant partitioning (C) isotherm. However, the interaction between taurultam and mammalian erythrocytes was shown to follow a Langmuirian (L) pattern. It is postulated that this difference may be due to the hydrolysis of taurultam by the bacterial cell after adsorption with the subsequent liberation of formaldehyde and the metabolite, taurinamide.
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