Abstract

Human herpesvirus-6 (HHV-6) is the etiological agent in most patients with a primary exanthem subitum infection, and it is often reactivated in immunosuppressed patients following hematopoietic stem cell transplantation (HSCT).1, 2 We report a female infant with ALL who developed primary HHV-6 infection during the early phase of allogeneic cord blood stem cell transplantation (CBSCT). The patient developed vesiculobullous eruptions that were indistinguishable from the skin lesions of acute GVHD. She was diagnosed with primary HHV-6 infection by virus isolation from the peripheral blood and detection of HHV-6 using the PCR. She was successfully treated with ganciclovir.

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