PRIMARY HYPERPARATHYROIDISM. A CLINICAL OBSERVA

Abstract

Background. Primary hyperparathyroidism is an endocrine disease resulting from a primary pathology of the parathyroid gland, characterized by increased secretion of parathyroid hormone and increased blood calcium levels. Among the endocrine diseases, primary hyperparathyroidism is the third most common after diabetes mellitus and thyroid disease. Without timely diagnosis, primary hyperparathyroidism causes systemic damage to internal organs: renal impairment, nephrolithiasis, esophageal affection, cardiovascular and nervous system and affects bones. The aim of the work was to present a clinical case of a patient with primary hyperparathyroidism and to analyze the stages of its diagnosis and treatment. Material and methods. We reviewed the relevant literature and analyzed the patient’s medical records. Results and Discussion. The patient had a complicated course of primary hyperparathyroidism of bone and visceral form. Despite of the slow progression and availability of screening methods, hyperparathyroidism was detected at the stage of complications. The efficacy of the therapy has been assessed. The underlying reasons that made it difficult to diagnose PHPT at an early stage, before the development of serious complications of internal organs were investigated. Conclusions: It can be assumed that our clinical case will increase the awareness of physicians, especially therapists, about the primary manifestations of this pathology and the challenges of its detecting and avoiding diagnostic errors.