Abstract
IntroductionGlioblastoma in the pineal region is extremely rare with only a few cases reported in the literature.Case presentationA 68-year-old man presented with a sudden deterioration manifesting as a headache, vomiting and gait disturbance. A magnetic resonance imaging study revealed a heterogeneously ring-enhanced mass in the pineal region. The mass was subtotally removed through the occipital transtentorial approach, and diagnosed as a glioblastoma.ConclusionWe discuss the clinical course, radiological findings and treatment strategies of pineal glioblastoma with a review of the relevant literature.
Highlights
Glioblastoma in the pineal region is extremely rare with only a few cases reported in the literature.Case presentation: A 68-year-old man presented with a sudden deterioration manifesting as a headache, vomiting and gait disturbance
This paper presents a case of glioblastoma arising in the pineal region and discusses its clinical course, radiological findings and treatment strategies with a review of the relevant literature
The patients reported with a magnetic resonance (MR) imaging of pineal glioblastomas demonstrate characteristic features
Summary
The pineal region consists of the pineal body, the posterior wall of the third ventricle, tela choroidea and velum interpositum. Glioblastoma, which is the most malignant and frequent glioma in brain tumors, is extremely rare in the pineal region with only 17 cases being reported in the literature [2-13]. T1-weighted sagittal (B) and gadolinium-diethylenetriaminepentaacetic acid enhanced axial (C and D) magnetic resonance images demonstrating a heterogeneously ring-enhanced mass with central necrosis in the pineal region and ependymal dissemination in the fourth ventricle. A further review of the pre-operative MR imaging study showed an enhanced mass in the fourth ventricle that was consistent with ependymal dissemination (Fig. 1D). Http://www.jmedicalcasereports.com/content/2/1/288 pineal glioblastoma consisted of nine women and six men aged from 5 to 68 years (mean, 39.3 years) Compared with those of germ cell or parenchymal tumors in the pineal gland, pineal glioblastomas occur in middle aged adults with a slight female preponderance.
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