Primary Giant Cell Tumor of Soft Tissue in the Mental Region

Abstract

Giant cell tumors of soft tissue (GCT-ST) are considered to be the soft tissue analogue of giant cell tumors of bone. Although the majority of GCT-ST cases manifest histologically benign features, special consideration is required because GCT-ST can occasionally demonstrate extensive local invasion or distant metastases. Here, we present an extremely rare case of GCT-ST arising from subcutaneous mental soft tissue, rapidly growing over the mandibular gingiva and bone, and lacking overtly malignant features in clinical, radiological and cytological findings.