Abstract
Primary follicular lymphomas of the small bowel generally present with small whitish nodules and masses or polyp-like lesions; cases with other morphologies are extremely rare. We experienced a case of primary follicular lymphoma that presented with small bowel stenosis. The lesion needed to be differentiated from other causes, such as bowel tuberculosis, non-steroidal anti-inflammatory drug-related ulcers, Crohn’s disease, small bowel ischemia, trauma, and idiopathic bowel stenosis, but endoscopic biopsies did not result in a definite diagnosis. Therefore, the lesion was surgically resected and, consequently, a diagnosis of follicular lymphoma of the small bowel was finally made. We report the characteristics and macroscopic findings of follicular lymphoma of the small bowel along with a review of relevant literature.
Highlights
The gastrointestinal tract is the most common site of extranodal non-Hodgkin’s lymphoma (NHL), and primary gastrointestinal NHL accounts for 30-40% of all extranodal NHL cases [1]
We report an unusual case of gastrointestinal follicular lymphoma (FL) that presented with small bowel stenosis, with the characteristics and macroscopic findings of small bowel FL, along with a review of the relevant literature
Recent studies have revealed the frequent involvement of the jejunum and ileum in patients with gastrointestinal FL due to the development of novel endoscopic modalities to investigate small bowels, such as double-balloon enteroscopy (DBE) or video capsule endoscopy (VCE)
Summary
The gastrointestinal tract is the most common site of extranodal non-Hodgkin’s lymphoma (NHL), and primary gastrointestinal NHL accounts for 30-40% of all extranodal NHL cases [1]. The most common subtypes of primary gastrointestinal NHL are mucosal-associated lymphoid tissue lymphoma or diffuse large Bcell lymphoma, while follicular lymphoma (FL) is a relatively rare disease, accounting for approximately 13% of gastrointestinal NHL cases [2,3,4]. We report an unusual case of gastrointestinal FL that presented with small bowel stenosis, with the characteristics and macroscopic findings of small bowel FL, along with a review of the relevant literature. How to cite this article Suzuki H, Hamada Y, Tanaka K, et al (January 15, 2022) Primary Gastrointestinal Follicular Lymphoma Presenting With Bowel Stenosis.
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