Abstract

BackgroundExtramedullary plasmacytomas account for 4% of all plasma cell tumors and occur mainly in the upper respiratory tract; gastrointestinal system involvement is rare. Extramedullary plasmacytoma of the colon with perforation has not been reported.Case presentationA 77-year-old woman with a 1-year history of lower abdominal pain and nausea was admitted to our hospital. An abdominal computed tomography scan revealed a sigmoid tumor with perforation. The patient underwent emergency surgery. Pathological examination led to a diagnosis of plasmacytoma of the colon. The patient did not undergo postoperative adjuvant chemotherapy. She has had no recurrence in 14 months of regular follow-up.ConclusionsWe have herein described a rare case of extramedullary plasmacytoma of the gastrointestinal tract with perforation involving the sigmoid colon.

Highlights

  • Extramedullary plasmacytomas account for 4% of all plasma cell tumors and occur mainly in the upper respiratory tract; gastrointestinal system involvement is rare

  • We report a rare case of primary isolated extramedullary plasmacytoma of the colon with perforation and describe the patient’s postoperative clinical course

  • Case presentation A 77-year-old woman with a 1-year history of lower abdominal pain and nausea was admitted to our hospital

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Summary

Introduction

Extramedullary plasmacytomas account for 4% of all plasma cell tumors and occur mainly in the upper respiratory tract; gastrointestinal system involvement is rare. Most such plasmacytomas occur in the nasopharynx or upper respiratory tract; only 10% of reported cases have involved the gastrointestinal tract. Primary isolated extramedullary plasmacytoma of the colon is extremely rare. No previous reports have described plasmacytoma of the colon with perforation. We report a rare case of primary isolated extramedullary plasmacytoma of the colon with perforation and describe the patient’s postoperative clinical course.

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