Abstract
This article focuses on the symptomatic and diagnostic problems of primary duodenal adenocarcinoma by way of two case reports and a literature review.The diagnosis of primary duodenal adenocarcinoma is often delayed because its symptoms may be absent until the tumor has progressed, thus leading to a delay of several months. Patients typically present with a long history of variable and vague symptoms, and many are diagnosed with advanced disease. As regards clinical manifestations, abdominal pain is the most frequent symptom. The majority of these tumors are found to have infiltrated the duodenal wall at presentation, with many being unresectable due to local and distal invasion.
Highlights
Primary adenocarcinoma of the duodenum is a rare tumor and represents 50% of adenocarcinoma of the small intestine Because of its non-specific clinical signs, it poses a problem of delayed diagnosis and management, its treatment is mainly based on surgery
We report the observations of two patients admitted with duodenal adenocarcinoma requiring radical surgical treatment for one and palliative treatment for the other
The abdominal-pelvic CT scan showed parietal thickening (Figure 1) of the lower second duodenum in theabove the papilla infiltrated by a heterogeneous process of 28 x 23 millimeters invaded the lower part of the head of the pancreas without invasion of the peridodenal fat with normal liver and commun bile duct
Summary
Primary adenocarcinoma of the duodenum is a rare tumor and represents 50% of adenocarcinoma of the small intestine Because of its non-specific clinical signs, it poses a problem of delayed diagnosis and management, its treatment is mainly based on surgery. We report the observations of two patients admitted with duodenal adenocarcinoma requiring radical surgical treatment for one and palliative treatment for the other
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