Abstract
Primary ductal adenocarcinoma is a rare subtype of adenocarcinoma. Literature review showed 13 cases of primary ductal adenocarcinoma of the lacrimal gland. We report a case of primary ductal adenocarcinoma of the lacrimal gland and review of literature highlighting its clinical presentation, histopathology including immunochemistry and overall outcome.
Highlights
Primary ductal adenocarcinoma of lacrimal gland (PDALG) has emerged as a distinct subtype of lacrimal gland adenocarcinoma [1] that accounts for 2% of all epithelial lacrimal gland tumors [2]
Ductal adenocarcinomas are known to have highly malignant nature with only 13 cases reported of lacrimal gland
We report a second case of PDALG in female and review of literature to describe the clinical, imaging and immunohistochemical features, management and prognosis of this malignancy
Summary
Primary ductal adenocarcinoma of lacrimal gland (PDALG) has emerged as a distinct subtype of lacrimal gland adenocarcinoma [1] that accounts for 2% of all epithelial lacrimal gland tumors [2] This neoplasm exhibits similar characteristics to ductal carcinoma of salivary gland and breast. We report a second case of PDALG in female and review of literature to describe the clinical, imaging and immunohistochemical features, management and prognosis of this malignancy. Computed tomography showed a relatively well-defined mass with diffuse enhancement in lacrimal gland region associated with erosion of roof of the orbit (Figure 1b). Our patient presented at 38 years and is the youngest case of PDALG reported till date. Five patients underwent tumor resection with globe-sparing surgery, orbital exenteration was done in 7 cases and post-operative radiotherapy was given in 7 cases (Table 1)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Clinical & Experimental Ophthalmology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
