PRIMARY DIFFUSE LARGE B-CELL LYMPHOMA OF THE MANDIBLE: A CASE REPORT

Abstract

This report presents an intraosseous lymphoma that was previously misdiagnosed as periodontal disease. After 3 months of periodontal treatment in a private clinic, a 51-year-old male patient was referred to the stomatology department presenting mandibular swelling and paresthesia lasting 4 months. In his previous history, the patient reported prostatic cancer treated 3 years ago. During intraoral evaluation, an extensive mass with teeth mobility in the right mandible was observed. The radiographic examinations showed an extensive osteolytic lesion, with no limits and cortical perforation in the mandible. The main clinical hypothesis was oral metastasis. An incisional biopsy was performed, and the immunohistochemistry established the diagnosis of diffuse large B-cell lymphoma. Six cycles of chemotherapy were given, resulting in complete remission of the tumor. After 7 months, the patient is under follow-up with no recurrence. Although uncommon in the oral cavity, lymphoma should be considered in the differential diagnosis. This report presents an intraosseous lymphoma that was previously misdiagnosed as periodontal disease. After 3 months of periodontal treatment in a private clinic, a 51-year-old male patient was referred to the stomatology department presenting mandibular swelling and paresthesia lasting 4 months. In his previous history, the patient reported prostatic cancer treated 3 years ago. During intraoral evaluation, an extensive mass with teeth mobility in the right mandible was observed. The radiographic examinations showed an extensive osteolytic lesion, with no limits and cortical perforation in the mandible. The main clinical hypothesis was oral metastasis. An incisional biopsy was performed, and the immunohistochemistry established the diagnosis of diffuse large B-cell lymphoma. Six cycles of chemotherapy were given, resulting in complete remission of the tumor. After 7 months, the patient is under follow-up with no recurrence. Although uncommon in the oral cavity, lymphoma should be considered in the differential diagnosis.