Abstract
To the Editor: In-transit metastases (ITM) and satellite lesions (S) are not captured in national registries. We performed a high-powered case-control study of the clinicopathologic characteristics of primary cutaneous melanoma (PCM) to identify microscopic features associated with subsequent development of ITM/S. After reviewing medical records of patients with ITM/S diagnosed from January 1, 2010, through December 31, 2014, at Mayo Clinic, Rochester, we then studied all patients (n = 27) who were at least 18 years old at the time of PCM diagnosis and later developed ITM/S without synchronous stage IV disease.
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