Abstract

Primary cutaneous marginal zone B-cell lymphoma is a very rare, indolent entity, classified in in the category of extranodal marginal zone B cell lymphoma, and which presents 2% of all cutaneous lymphomas. It is an entity with several clinical characteristics and evolutionary, and especially histological, sometimes common with other neighboring entities, and posing above all the problem of positive and differential diagnosis. We expose a case of PCMZL with a particular presentation and difficulty of diagnosis over several years, insisting us through our observation on the necessity of repeating the anatomopathological examination with Immunohistochemistry to be able to make the diagnosis. The treatment is not codified, the therapeutic modalities proposed by the experts are many and varied.

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