Abstract
Primary cutaneous diffuse large B cell lymphoma is a rare and aggressive form of primary cutaneous B-cell lymphoma. It typically presents with reddish to brown-nodules on the distal legs. We introduce the case of a 71 year-old female who presented to an urgent care clinic with a new onset of painful nodules on her right lower extremity. After workup and treatment for superficial thrombophlebitis, the patient improved until she presented to her primary care physician with worsening symptoms one month later. Diagnosis of primary cutaneous diffuse large B-cell lymphoma, leg type was confirmed via biopsy. After referral to oncology, further workup showed stage 4 disease. The patient was subsequently scheduled to begin treatment with R-CHOP. Unfortunately, prior to the initiation of chemotherapy she passed away after contracting COVID-19 pneumonia.
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