Abstract
A 6-year-old otherwise healthy female presented to the ED with a right eyebrow lesion for one month. Previous I&D attempts and empiric antibiotic treatment had failed to improve the lesion. Following dermatology referral, superficial culture resulted with growth of Cryptococcus neoformans after which completion of oral fluconazole treatment resolved the lesion. Though Cryptococcus neoformans infections commonly plague immunocompromised patients, primary cutaneous cryptococcosis in the immunocompetent patient is a rare but documented infection with a paucity of reported pediatric cases, and frontline physicians should be aware of such a diagnosis in the setting of persistent skin lesions without response to more commonly utilized therapies.
Highlights
Primary cutaneous cryptococcosis (PCC) refers to an infectious process seen in immunocompetent patients wherein cryptococcal organisms directly inoculate the skin by exposure, typically in unclothed areas
A 6-year-old female presented to the ED with the complaint of a right eyebrow “abscess” for one month prior to presentation (Figure 1)
Primary cutaneous cryptococcosis (PCC) is defined as direct inoculation and infection of the skin, and it is a rare condition in immunocompetent patients
Summary
Mitchell Hobbs MDa, Joy King MD PhDb, Rana El Feghaly MD MSCIc, Robert Brodell MDd aUniversity of Mississippi School of Medicine, Department of Pediatrics bUniversity of Mississippi School of Medicine, Department of Pathology cUniversity of Missouri-Kansas City School of Medicine, Department of Pediatrics dUniversity of Mississippi School of Medicine, Department of Dermatology
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