Abstract
Blastic natural killer-cell lymphoma, also called “agra-nular CD4+ CD56+ haematodermic neoplasm” is an uncommon type of tumour, which is included in the new World Health Organization (WHO) classification as a malignancy derived from natural killer (NK) cells. It is very aggressive, affecting many organs, and skin involve-ment is highly characteristic. Several origins have been proposed, but recent studies have shown a relationship with plasmocytoid monocytes.We report here a new case of this rare lymphoma, with skin infiltration as the first manifestation, and with early dissemination to bone marrow and central nervous system (CNS). CASE REPORT
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