Abstract
Adenosquamous carcinoma is an aggressive and rare variant of squamous cell carcinoma that has both squamous and glandular differentiation. We present a case of occipital scalp adenosquamous carcinoma in a 43-year-old male who presented with occipital mass that was initially marble in size, which progressively enlarges over years. There were no constitutional symptoms. No neurological deficit and locoregional lymph nodes were not palpable. Contrast enhanced computerized tomography brain revealed a non-enhancing midline occipital scalp mass with no intracranial extension or bony involvement. Tissue biopsy of the occipital mass was performed, and preliminary microscopic and immunohistochemistry studies suggested adenosquamous carcinoma. The tumor was completely excised with wide local excision, followed by skull burring and primary closure.
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