Primary cilia and regulation of renal Na+ transport. Focus on “Heightened epithelial Na+ channel-mediated Na+ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia”

Abstract

primary cilia (PC) are solitary, phallus-like structures that protrude into the extracellular environment from the surface of a surprisingly large number of different cell types (see Ref. [15][1] for a recent review), including most epithelial cells. They are generally nonmotile, apart from a