Abstract
Of recent years, several investigators have described the eye disease which occurs in rats as the result of diets deficient in fat-soluble A. Various names have been given to this condition. McCollum and Simmonds1termed it xerophthalmia. They chose this name after careful study of the development, symptoms and treatment of xerophthalmia as it occurs in rats and man. Osborne and Mendel2preferred to use the more general term ophthalmia. Goldschmidt3studied the pathology of the disease as it occurred among young rats on Hopkins' diet. His studies convinced him of the identity of the lesion with keratomalacia in man, and he proposed giving this name to the disease in the rat. Stephenson and Clark4also preferred this term to xerophthalmia, for the pathologic condition in the eyes of rats seemed to them to resemble keratomalacia more
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
