Abstract
Background: Primary choriocarcinoma of the cervix is a very rare entity. Case: A 35-year-old patient had been admitted to our hospital with vaginal bleeding for 7 months. A cervical mass measured 4 × 4 cm was palpated on the anterior surface of the cervix. Biopsy of the lesion demonstrated extensive necrosis and was in favor of squamous cell carcinoma. Patient was accepted as FIGO stage Ib1-2 and underwent type II hysterectomy with bilateral salpingoopherectomy and bilateral pelvic lymph node dissection was carried out. Post operative pathologic evaluation of the surgical specimen evinced that the case was primary cervical choriocarcinoma. Conclusion: Primary choriocarcinoma of the cervix should be considered in patients in their reproductive years with cervical lesion and negative cervical cytology. Beta-hCG assay and transvaginal color Doppler sonography are useful for early diagnosis.
Highlights
Choriocarcinoma was categorized into two classes: gestational and non gestational
Post operative pathologic evaluation of the surgical specimen evinced that the case was primary cervical choriocarcinoma
Primary choriocarcinoma of the cervix should be considered in patients in their reproductive years with cervical lesion and negative cervical cytology
Summary
Non gestational choriocarcinoma is a rare germ cell tumor of the ovary that only few cases are reported in literature. Most of the extrauterine choriocarcinoma reported in literature, originates in uterine cervix [2,3,4,5,6,7]. Our objective was to describe the clinical and pathologic findings of one case of primary cervical choriocarcinoma in a 35-year-old woman and reviews of the literatures. Primary choriocarcinoma of the cervix is a very rare entity. Post operative pathologic evaluation of the surgical specimen evinced that the case was primary cervical choriocarcinoma. Conclusion: Primary choriocarcinoma of the cervix should be considered in patients in their reproductive years with cervical lesion and negative cervical cytology. Beta-hCG assay and transvaginal color Doppler sonography are useful for early diagnosis
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