Primary carcinoma of the liver: report of 20 cases, including two treated with triethylene melamine.

Abstract

Article1 July 1954PRIMARY CARCINOMA OF THE LIVER: REPORT OF 20 CASES, INCLUDING TWO TREATED WITH TRIETHYLENE MELAMINEHENRY M. WILSON, M.D.HENRY M. WILSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-1-118 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTwenty cases of primary carcinoma of the liver have been found in 35,995 admissions to this hospital in the last 10 years. Twelve of these patients had hepatomas, or liver cell tumors, while six had cholangiomas, or bile duct cell tumors, and two had atypical or mixed types. The ratio of hepatomas to cholangiomas, therefore, was 2:1, which agrees with the ratio given by Bockus.1 Ten of these 20 patients (seven of the hepatoma group and three of the cholangioma group) also had cirrhosis. Seven were white males and 13 were Negro males.Since primary carcinomas of the liver grow...Bibliography1. Bockus HL: Gastro-enterology, Vol. 3, 1946, W. B. Saunders Co., Philadelphia, p. 357. Google Scholar2. LewisCrossley MRML: Retardation of tumor growth in mice by oral administration of ethylenimine derivatives, Arch. Biochem. 26: 319, 1950. MedlineGoogle Scholar3. KarnofskyBurchenalArmisteadSouthamBernsteinCraverRhoads DAJHGCCMJLLFCP: Triethylene melamine in the treatment of neoplastic disease; a compound with nitrogen mustard-like activity suitable for oral and intravenous use, Arch. Int. Med. 87: 477, 1951. CrossrefGoogle Scholar4. BurtnerJensenRumball OWLCJM: Triethylene melamine in the treatment of lymphomas and other neoplastic diseases, Ann. Int. Med. 38: 1222, 1953. LinkGoogle Scholar5. Ruegsegger JM: Personal communication. Google Scholar6. StrongPittsMcPhee GFHHJG: Primary carcinoma of the liver—25 year study, Ann. Int. Med. 30: 791, 1949. LinkGoogle Scholar7. Goldenberg IS: Carcinoma of the biliary tract, Am. J. Surg. 86: 292, 1953. CrossrefMedlineGoogle Scholar8. Lemmer KE: Primary carcinoma of the liver, Arch. Surg. 61: 599, 1950. CrossrefGoogle Scholar9. Gustafson EG: An analysis of 62 cases of primary carcinoma of the liver, Ann. Int. Med. 11: 889, 1937. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Peoria, Illinois*Received for publication December 28, 1953.The triethylene melamine was furnished by J. M. Ruegsegger, M.D., Lederle Laboratories, Pearl River, N. Y.From the Medical Service, Veterans Administration Hospital, Alexandria, Louisiana. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDNA Alkylating Agents 1 July 1954Volume 41, Issue 1Page: 118-123KeywordsBile ductsCirrhosisHepatocellular carcinomaLiverMedical servicesPathologistsRivers Issue Published: 1 July 1954 PDF downloadLoading ...