Abstract
Angiosarcomas of the breast are rare parenchymal malignancies of the chest wall. Surgery is the main treatment modality with chemotherapy and radiotherapy used in case of recurrence. With generally unfavourable prognosis and lack of clear treatment guidelines due to its rarity and scarcity of available data, angiosarcoma of the breast is a challenging clinical situation for both oncologist and patient. We present here the results of a series of 11 consecutive primary angiosarcoma cases treated at our institute between 2000 and 2015.
Highlights
Angiosarcomas are exceedingly rare and highly aggressive breast tumours that occur in less than 0.05% of patients with malignant tumour within this organ[1]
We can distinguish two main types of angiosarcomas affecting the breast: the primary angiosarcoma developing de novo and secondary angiosarcoma developing as a consequence of previous breast cancer treatment
During the period of 16 years, a total of 11 patients diagnosed with primary breast angiosarcomas were seen and treated at the Department of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology (Table I)
Summary
Angiosarcomas are exceedingly rare and highly aggressive breast tumours that occur in less than 0.05% of patients with malignant tumour within this organ[1]. Amongst adult patients diagnosed with soft tissue sarcoma, primary breast angiosarcoma accounts for approximately 2% of cases[3]. It is most commonly seen in younger patients, women in their thirties and forties[4]. Due to the highly aggressive course of the disease and its tendency to have local recurrence and distant metastasis, other treatment methods such as chemotherapy or radiotherapy should be used, under the supervision of a multidisciplinary team
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