PRIMARY ADENOSQUAMOUS CARCINOMA OF COLON – A RARE CASE DIAGNOSED ON HISTOPATHOLOGY

Abstract

Introduction: Primary Adenosquamous carcinoma is a rare colorectal tumour with both an adenocarcinoma and a squamous cell carcinoma component. To the best of our knowledge, only few cases have been reported in the literature. [2,5] Adenosquamous carcinoma of the colon accounts for 0.02%–0.06% of all colorectal malignant tumours . Case Presentation: We report a case of a 70-year-old woman, hospitalized for acute abdominal pain, fever, vomiting and constipation. Ultrasonography revealed perforated gall bladder. Exploratory laparotomy revealed liver intestinal adhesions, mass lesion in transverse colon and liver abscess. Transverse colon was resected and liver abscess was drained. Resected transverse colon was sent for histopathological evaluation, which revealed Adenosquamous carcinoma of intestine. Patient was discharged after post-op stabilization and sent to higher centre for further treatment. Discussion: Primary Adenosquamous carcinoma is a rare colorectal neoplasm revealed by non-specific complaints. Its clinicopathology is not yet understood. Preoperative diagnosis is often difficult. Surgical resection remains the mainstay of treatment. Primary Adenosquamous carcinoma is a malignant tumour with poorer prognosis than Conclusion: adenocarcinomas. Histopathological evaluation is indispensable for diagnosis of Primary Adenosquamous carcinoma as its clinical presentation is non-specific, so that appropriate treatment can be provided.