Abstract
Primary fallopian tube cancer is the rarest cancer of female genital tract. In fact, it represents less than 1% of all the gynaecological and breast cancers. Adenocarcinoma is the most common histological type. This paper revels two cases of primary fallopian tube adenocarcinoma. They are diagnosed in pathology department. There are two patients to 53 years and 62 years respectively, with no significant personal or family history. They are consulted for chronic pelvic pain with pelvic mass. The clinical assessment revealed an abdomino-pelvic mass of hard consistency. We review the epidemiological, clinical, anatomo-pathological, therapeutic and prognosis specificities of this tumor. This cancer occurs in patients in their sixties, in a context of infertility, pauci-parity, chronic tubal infection or a genetic predisposition. The pelvic pain and the perception of a pelvic mass are the most frequent clinical manifestations. Paraclinical examinations (pelvic ultrasound, CT, MRI and serum markers) are not specific and diagnosis is often made peroperatively or postoperatively by anatomo-pathological examination. In fact, the tubal carcinoma is often confused with his ovarian counterpart which have several similarities. The prognosis is relatively dark, but still better than ovarian carcinoma. It mainly depends on the stage of disease and quality of surgical resection.
Highlights
A malignant epithelial tumour of the tubal mucosa has usually a glandular differentiation
In order to be considered a primary carcinoma of the fallopian tube, the tumour must be located macroscopically within the tube or its fimbriated end, and the uterus and ovary must either not contain carcinoma
Primary fallopian tube carcinoma as first described by Reynaud [4]. It is associated with chronic tubal inflammation, infertility, tuberculous salpingitis and tubal endometriosis [5]
Summary
A malignant epithelial tumour of the tubal mucosa has usually a glandular differentiation. The pathological diagnosis showed a papillary proliferation infiltrating fallopian tube with moderate atypical cells with a mitotic index at 20 mitoses/10 HPF. They were peritoneal nodules >2 cm, adnexa controlateral, uterine corpus and cervix were histologically normal. Abdomino- pelvic CT scan showed a left latero-uterine tissue mass with necrosis, slightly enhanced by injection of contrast (Figure 3). They were peritoneal nodules with an over density of mesenteric fat. Cells have atypical nuclei with a mitotic index at 24 mitoses/10 HPF They were peritoneal nodules >2 cm, left ovarium, right adnexa, and uterine corpus and cervix were histologically normal.
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