Abstract
Methods Study design: Quasi-experimental. Time period: January 2008-March 2013. Setting: IMS Health retail quarterly trade prices from the private sectors in Mexico and Brazil. Groups studied were: antibiotics, cough-and-cold medicines, non-steroidal antiinflammatory drugs (NSAIDs), and analgesics. The latter two groups were combined in the analysis of median price per defined daily dose (DDD). All prices were adjusted for inflation rate and converted to US Dollars. Interventions: Interrupted time series analysis to measure price changes (level and slope) after the OTC sales regulation of antibiotics and seasonal price changes. Stationarity and autocorrelation corrected using ARIMA models.
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