Abstract
Platelet-rich fibrin (PRF) is a blood concentrate system derived from human peripheral blood. A solid and a liquid PRF-based matrix can be obtained by centrifugation in accordance with specific centrifugation protocols without the addition of anticoagulants or external chemicals. In dentistry, oral- and cranio-maxillo-facial surgery, PRF-based matrices are used on different subjects. The healing benefits of platelet-rich preparations together with the low risk profile and disposability of a simple preparation procedure should encourage more clinicians to incorporate PRF as a treatment option in their practice to accelerate healing, reduce adverse events, and improve patient outcomes.
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