Previous Percutaneous Coronary Intervention Does Not Increase In-Hospital Mortality After Surgical Revascularization: Analysis of 63420 Cases

Abstract

Background Recent publications indicate higher in-hospital mortality following myocardialrevascularization in patients with previous history of successful percutaneouscoronary intervention. Yet, no risk models of surgical mortality have includedpercutaneous intervention as a risk factor. Objectives The purpose of this study was to analyze whether previous percutaneous coronaryintervention is a risk factor of in-hospital mortality in coronary artery bypassgrafting. Methods The study included 78794 patients retrieved from the Spanish Ministry of Healthdatabase, who underwent coronary artery bypass graft surgery between January 1997and December 2007. After applying exclusion criteria, 63420 patients were includedin the study, 2942 (4.6%) of whom had previously undergone percutaneous coronaryintervention. Continuous variables were compared using the Mann-Whitney U testor Student’s t test, and categorical variables using the chi-square test. Univariateand multivariate logistic regression analyses and a multivariate analysis including apropensity score were performed. Results Previous percutaneous coronary intervention was not an independent risk factor ofin-hospital mortality in the multivariate logistic regression analysis (odds ratio 0.88;95% confidence interval, 0.72-1.07; p=0.20) or after adjusting for propensity score(odds ratio 0.9; 95% confidence interval, 0.75-1.08; p=0.27). Conclusion Previous percutaneous coronary intervention is not an independent risk factor of inhospitalmortality in patients undergoing coronary artery bypass grafting.