Abstract

A study was made of the efficacy of local antibiotics in the prevention of postoperative wound infections in 354 recipients of renal transplants. There was a statistically significant difference in the rates of wound infection between patients treated with and patients treated without antibiotics, in both primary and secondary wounds. No deleterious local or systemic side effects occurred. From this study we conclude that local antibiotics, such as bacitracin and neomycin, should be used for all wounds in transplant recipients, and their use in other types of surgery is recommended. A study was made of the efficacy of local antibiotics in the prevention of postoperative wound infections in 354 recipients of renal transplants. There was a statistically significant difference in the rates of wound infection between patients treated with and patients treated without antibiotics, in both primary and secondary wounds. No deleterious local or systemic side effects occurred. From this study we conclude that local antibiotics, such as bacitracin and neomycin, should be used for all wounds in transplant recipients, and their use in other types of surgery is recommended.

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